Toggle menu

BRAINED – TBI

Start date:
16/11/2020
Main trial site:
Royal Infirmary of Edinburgh

There are approximately 300 CT head scans ordered from the Emergency Department (ED) at Royal Infirmary of Edinburgh per month; many of which indicate that there is no significant injury.

A blood-based brain biomarker test that can predict presence or absence of a brain injury and its severity would support clinical decision making and reduce the need for CT scans, streamline clinical management, reducing costs and cranial exposure to radiation. In this study blood samples will be collected from participants for whom the assessing clinician has identified a clinical need to undergo CT brain imaging after a TBI, and where patients have given consent to participate in the NHS Lothian Biobank. Blood samples will be anlaysed using infrared spectroscopy, or other assays targeted at TBI assessment. Our aim is to ascertain whether the severity and likely clinical course of a head injury can be accurately predicted at the time of admission.

Research Team

Polly Black

Senior Research Nurse

More EMERGE Trials

ISARIC4C – Coronavirus Clinical Characterisation Consortium, an observational study

ISARIC/WHO Clinical Characterisation Protocol for Severe Emerging Infections in the UK (CCP-UK)

Diagnostics devices play an important part in the clinical assessment of a patient’s health and treatment. The purpose of the study is the evaluation of a new diagnostic platform developed by LumiraDx. The evaluation is focused around various biomarkers useful in the emergency settings.

Read more

NOVEL Study

Collection of venous and capillary blood samples for the evaluation of new diagnostic devices for cardiovascular conditions

DASH Trial

DASH is a randomised clinical trial investigating a treatment to reverse the effects of blood-thinning medications.