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Repurposing flumazenil for pre-hospital intramuscular treatment of coma due to recreational drug overdose; 01 October 2023 (54 months). DPFS MRC Biomedical Catalyst Reference: MR/X030237/1; £2,853,402. Co-Applicant Matt Reed, CI Professor Michael Eddleston

ASES (Aortic Syndrome Evidence Synthesis): HTA 21/555 Health Technology Assessment Programme Researcher-led (evidence synthesis): Diagnostic strategies for suspected acute aortic syndrome (AAS): Evidence synthesis and value of information analysis; £190,771; 01/11/2022 to: 31/10/2023 (12 months) Co-Applicant Matt Reed, (CI S Goodacre)

BHF Project Grant PG/21/10805. Qualitative study to explore the acceptability of an accelerated syncope strategy to patients and staff involved in the ASPIRED trial. Chief Investigator Matt Reed £22,004.11

CIHR project grant. Evaluating a selective CT head scanning approach in anticoagulated head-injured emergency department patients. Co-applicant Matt Reed (CI K de Wit), July 2021, 5 years; CAN$ 1,239,300 (£718,050)

BHF Clinical Study; £1,303,649.37. A multi-centre open label randomised controlled trial of a 14 day ambulatory ECG patch monitor versus standard care in emergency department unexplained syncope patients: The ASPIRED study. Chief Investigator Matt Reed, January 2021

NIHR HTA: DENS Study: NIHR131118 DENS RCT: Duration of External Neck Stabilisation following odontoid fracture in older or frail adults: a randomised controlled trial of collar versus no collar. Call: 19/82 Conservative management of odontoid fracture in the elderly: to immobilise or not? £2,014,760, Co-applicant Matt Reed (CI P Brennon), December 2020

Wellcome Trust ISSF3. Multimorbidity and Emergency Healthcare Provision: Improving Care through Data Driven Innovation (£39,056), Co-applicant Matt Reed (CI Nazir Lone), January 2020

NIHR Brain Injury MedTech Co-operative Seedcorn Funding Competition 2019. Using fourier transform infrared spectroscopy for head injured patients. (£10,000). Co-applicant Matt Reed (CI Paul Brennon) September 2019 (1 year)

DTP Precision Medicine. Delirium as an acute brain injury in hospital inpatients: can clinical features and biomarkers predict outcomes? (£45,027). Co-applicant Matt Reed (CI MacLullich AMJ), January 2020

NIHR Brain Injury MedTech Co-operative Seedcorn Funding Competition 2019. Delivery of digital cognitive behavioural therapy following concussion (feasibility study). (£10,000). Co-applicant Matt Reed (CI Aimun Jamjoom) September 2019 (1 year)

Previous

2018-2019

  1. Medical Research Council; Confidence in Concept. Development of a novel wearable device to secure peripheral intravenous cannulas. 108,598). Co-applicant Matt Reed (CI Ashton Barnett-Vanes) 2019 (12 months).

2017-2018

  1. Reed MJ. Chief Scientist Office (Scotland) NRS Career Researcher Clinician Award(April 2017 – March 2019): approximate total value £43,000
  2. Wardlaw J, Whiteley W, Dennis M, Al-Shahi Salman R, Macleod M, Gray A, and Reed MJ. Chief Scientist Office Research Grant.  What is the best brain imaging strategy for patients with suspected minor stroke or transient ischaemic attack (TIA)?(£372,494), Co-applicants; Co-Investigator 2017 (30 months)
  3. High-Sensitivity Cardiac Troponin On Presentation to Rule Out Myocardial Infarction (HiSTORIC) trial. Mills N, Newby DE, Berry C, Shah A, Gray A, Maguire D, McAllister D, Parker. The Historic Trial. BHF project grant. £271,484 (2015-18). Roles: Co-applicant, local collaborator, steering group member.
  4. Mills M, Gray A, Newby D, Norrie J, Goodacre S, Thokala P, Roditi G, Byrne J, Lowe D, Shah A, Lee K. Troponin in Acute chest pain to Risk stratify and Guide EffecTive use of Computed Tomography Coronary Angiography (TARGET-CTCA). £1,118,723. BHF Project Grant (2018-2024). Roles: Co-chief investigator, steering group member.
  5. Small Business Research Initiative (SBRI). SNAP40-ED. Detection of physiological deterioration by the SNAP40 wearable device compared to standard monitoring devices in the ED (£167,479), Grant holder Matt Reed; CI 2017
  6. Richardson, S & Odam, M. Project Sachibondu: Where there is no doctor. Laerdal Foundation £39,050

2016-2017

  1. Clegg G. Public Accessible Defibrillators (PADs) Modelling Analysis Project – 2017/18 £29,494 – Awarded
  2. Clegg G. Scottish Resuscitation Academy and Scottish Cardiac Arrest Symposium 2016 — Health Foundation, Spreading Improvement; Supporting Dissemination award £28,705 – Awarded
  3. Dear J. Principal Investigator, Hepato-renal molecular signalling by microRNA-122, Cunningham Trust, £82,640 – Awarded
  4. Dear J. Principal Investigator, Development of microRNA-19 as a marker, mediator and treatment for liver injury, Medical Research Scotland, £111,085 – Awarded
  5. Dear J. Principal Investigator, Randomised Open Label Exploratory, Safety and Tolerability Study with PP100-01 in patients treated with the 12-hour Regimen of N-Acetylcysteine for Paracetamol/Acetaminophen overdose, Pledpharma AB, £500,000 – Awarded
  6. Dear J. Principal Investigator, Extra-cellular vesicles and microRNA as markers and mediators of human vascular inflammation, British Heart Foundation, £110,000 – Awarded
  7. The Role of Multidetector Computed Tomography Coronary Angiography In Emergency Department Patients With Suspected Acute Coronary Syndrome. A Gray, C Robottom, S Goodacre, D Newby, J Smith, S Lewis, A Fletcher, R Storey, P Thokala. HTA programme, DOH £2,050,000. HTA programme (2014- 2021). Roles: Chief investigator, steering group member, writing group chair, project management group chair.
  8. Development and validation of the 4AT: a new triage tool for delirium. A McLullich, C Fox, M Godfrey M, J Hanley, N Siddiqu, Weir C, J Young, S Shenkin, A Gray, J Smith, A Anand, T Ryan. £827,431. HTA programme. (2014-17). Roles: Co- applicant and investigator
  9. High-Sensitivity Cardiac Troponin On Presentation to Rule Out Myocardial Infarction (HiSTORIC) trial. Mills N, Newby DE, Berry C, Shah A, Gray A, Maguire D, McAllister D, Parker. The Historic Trial. BHF project grant. £271,484 (2015-18)
  10. Reed MJ. Chief Investigator, Diagnostic yield of an ambulatory patch monitor in Emergency Department syncope patients unexplained after Emergency Department evaluation – a pilot study (PATCH-ED), Chest Heart and Stroke Scotland, £4,900
  11. Reed MJ. Chief Investigator, The Emergency Medicine Annotated Bioresource consortium (EM-ABC): A pilot and feasibility programme, Edinburgh and Lothian Grants Programme, £37,212
  12. Reed MJ. Chief Investigator, Introduction of paramedic led Echo in Life Support (ELS) into the pre-hospital environment, Resuscitation Council, £19,718
  13. Reed MJ. Co-Chief Investigator, A double blind randomised placebo controlled trial of topical Aloe Vera Gel in Emergency Department patients presenting with simple traumatic wounds (The ALOE study), Edinburgh and Lothian Grants Programme, £20,000
  14. Reed MJ. Co-Chief Investigator, A double blind randomised placebo controlled trial of topical Aloe Vera Gel in Emergency Department patients presenting with simple traumatic wounds (The ALOE study), Royal College of Emergency Medicine, £5,700
  15. Reed MJ. Chief Investigator, Randomised control trial of a smart phone based event recorder for patients presenting to the Emergency Department with palpitations and pre-syncope – The IPED (Investigation of Palpitations in the ED) study, Chest Heart and Stroke Scotland, £23,056
  16. Reed MJ. British Heart Foundation. The IPED (Investigation of Palpitations in the ED) study: Randomised controlled trial of the use of a smart phone based event recorder versus standard care for patients presenting to the Emergency Department with palpitations and pre-syncope. (£21,347). Grant holder; Chief Investigator 2017 (12 months)
  17. Reed MJ. Chief Investigator, SNAP40-ED: Detection of physiological deterioration by the SNAP40 wearable device compared to standard monitoring devices in the Emergency Department, Small Business Research Initiative for Healthcare Development, £228,616

2015-2016

  1. Black P. Attendance at International Emergency Nurse Conference, SRNCN £150
  2. Gallagher B. Masters in Public Health Study 2015-16, GNC 2016 £2,025
  3. Gowens PA. Health Foundation Small Grant award £5250
  4. Gowens PA. Health Foundation Spreading​ ​Improvement Grant £28,705
  5. Grahamslaw J. RCN International Research Nursing conference May 2015. £220 Elsie Inglis Staff Development Award. £224 Medic One.
  6. The Role of Multidetector Computed Tomography Coronary Angiography In Emergency Department Patients With Suspected Acute Coronary Syndrome. Gray A, Robottom C, Goodacre S, Newby D, Smith J, Lewis S, Fletcher A, Storey R, Thokala P. HTA programme, DOH £2,050,000. HTA programme (2014- 2019). Roles: Lead applicant and investigator, steering group member, writing group chair, project management group chair.
  7. Development and validation of the 4AT: a new triage tool for delirium. McLullich A, Fox C, Godfrey M, Goodacre S, Hanley J, Siddiqi N, Weir C, Young J, Shenkin S, Gray A, Smith J, Anand A, Ryan T £827,431. HTA programme. (2014-17). Roles: Co-applicant and investigator
  8. EM-ABC. Gray A, Reed M, Clegg G, Masson M. Edinburgh and Lothian Health Foundation – Research Grants. £37,212.00. (2013-15). Roles: Lead applicant and co-investigator.
  9. Mills N, Gray A et al. The Historic Trial. BHF project grant. £250,233 (2015-18). Roles: Co-applicant
  10. MacRaild A, Steven J. 4AT Study Grant. Attendance at Geriatric Emergency Medicine Conference. £590
  11. O’Brien R. RCN International Research Nursing conference May 2015. £220 Elsie Inglis Staff Development Award. £224 Medic One.
  12. O’Brien R. Attendance at RCEM Annual Scientific Conference September 2015. £220 Elsie Inglis Staff Development Award. £150

2014-2015

  1. Reed MJ. Serial Brain Natriuretic Peptide (BNP) measurement in syncope.  Chief Scientist Office Small Grant, £3,525.  Final report graded Satisfactory.
  2. Lyon RM.  Peel Medical Research Trust, £2000.
  3. Skinner J, Maran N. Significant Event Analysis: a reflective tool for undergraduate medical students. Clinical Skills Managed Educational Network, £4,400.
  4. MacLeod M, Skinner J. Critical incident training: does interdisciplinary training enhance critical decision making and team performance. Clinical Skills Managed Educational Network, £3,900.
  5. S Goodacre, M Campbell, J Nicholl, J Radcliffe, S Holgate, A Gray, T Coats, J Benger, P Jackson. The 3MG Trial: Randomised controlled trial of intravenous or nebulised magnesium sulphate or standard therapy for acute severe asthma National Health Technology Assessment programme, Department of Health £1,727,163 (2007-2010).
  6. N Bateman, R Thanacoody, A Gray, S Thomas, M Eddleston, D Webb. Scottish and Newcastle Antiemetic Pre-treatment for Paracetamol Poisoning (SNAP) trial. CSO programme. £191,186. (2010-2012).

Prior to 2014

  1. Is Rotational Thromboelastometry (ROTEM) useful to detect Occult Coagulopathy in the Emergency Department? (£6,624), Matt Reed Grant holder & CI 2010
  2. Chief Scientist Office Small Grant CZG/2/444 – Serial Brain Natriuretic Peptide (BNP) measurement in syncope. (£3,525): Final report graded Satisfactory, Matt Reed Grant holder & CI 2009
  3. CEM/BAEM Clinical Effectives Committee Research Grant – Prediction of Risk in Syncope using Electrocardiograph characteristics: a PILOT study (£1,721), Matt Reed Grant holder & CI 2007
  4. Chief Scientist Office Clinical Academic Training Fellowship CAF/06/0. Risk stratification Of Syncope in the Emergency department (£115,566). Final report graded Excellent, Matt Reed Grant holder & CI 2006