Alison Williams
Senior Research Nurse
I qualified in 2001 with a Diploma in Adult Nursing. I have the fondest memories of my first post in Orthopaedics growing in confidence, nursing skills and establishing fundamental nursing values and appreciation of my nursing role and duty of care.
A passion for acute medicine then took me to the Emergency Department and this has been my home for the last 13 years. I have always loved the fast pace and variety the ED offers working within a tight team of staff.
After 10 years of working as a ED staff nurse I expanded my scope of practice in the role of acute nurse practitioner. I have enjoyed working autonomously within a small team seeing and treating a variety of medical needs and gaining valuable knowledge and skills.
I have always had a curiosity about research and actively engaged with and supported ongoing trials/studies within the ED. This curiosity recently led me to apply for a post with the EMERGE team which I was very lucky to have been offered and here I am.
I am so excited to join such a highly respected and established research team within the Emergency Department. I hope to bring my experience, passion and enthusiasm for emergency medicine to my new post.
Trials
Early diagnosis is central to improving outcomes for patients with cancer. For cancers without specific risk factors, or with no screening programs are difficult to diagnose and patients often present with non-specific symptoms. Unfortunately this means that these patients are often diagnosed late on in the development of the disease and treatment options are reduced.
INFERENCE
This trial is an open label two-arm randomised trial focused on identifying the best treatment for community acquired sepsis patients. We will be investigating the feasibility of delivering early intravenous fluid resuscitation by comparing 5% human albumin solution (HAS) to balanced crystalloid. Currently, balanced crystalloids are used as routine care and the first line therapy in the international sepsis guidelines, whereas HAS is the second line fluid therapy in septic shock. Although, studies are showing that HAS may have further potential benefits to patients with sepsis.
ABC SEPSIS
ABC SEPSIS
To determine the association between high-sensitivity cardiac troponin concentration and obstructive coronary artery disease in patients presenting to the Emergency Department with suspected acute coronary syndrome and cardiac troponin concentration within the normal reference range using CTCA.
PRECISE-CTCA Trial
To determine the association between high-sensitivity cardiac troponin concentration and obstructive coronary artery disease in patients presenting to the Emergency Department with suspected acute coronary syndrome and cardiac troponin concentration within the normal reference range using CTCA.
EHA - Epidemiological analysis for the Hereditary Angioedema Disease is an international, multicentre, epidemiological study that aims to explore the feasibility of a new Dried Blood Spot (DBS) filtercard-based screening algorithm and thereby the prevalence of the Hereditary Angioedema.
EHA Study
EHA - Epidemiological analysis for the Hereditary Angioedema Disease
Assisting in identifying patients with Humeral shaft fractures in the ED by screening.
Giving patient information sheets to introduce the study, so patient has had adequate time to read and make decision about going into the trial before going to the fracture clinic.
HU-FIX Trial
Minimal Unit Pricing Study (MUP)
Assessing the impact of the Minimum Unit Pricing
Diagnostics devices play an important part in the clinical assessment of a patient’s health and treatment. The purpose of the study is the evaluation of a new diagnostic platform developed by LumiraDx. The evaluation is focused around various biomarkers useful in the emergency settings.
NOVEL Study
Collection of venous and capillary blood samples for the evaluation of new diagnostic devices for cardiovascular conditions
ATTEST2 Trial
Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis (ATTEST 2)
This is a study looking at incidence and risk factors for poor ankle functional recovery, and the development and progression of post-traumatic ankle osteoarthritis after significant ankle ligament injury.
SALI Study
SALI study - Significant Ankle Ligament Injury