Toggle menu

TPTIH

Start date:
August 2015
End date:
Predicted September 2017
Co-ordinated by:
The University of Nottingham

To establish genetic associations between patients with thiazide-induced hyponatraemia and patients taking a thiazide who did not develop hyponatraemia.

Eligibility criteria

Inclusion criteria:

  • Age 18-100 years
  • Have the capacity to give informed consent
  • Be taking a thiazide or thiazide-related diuretic unless in the non-thiazide control group
  • Plasma sodium concentration of less than 130 mM for cases and between 135 mM and 145 mM for controls

Local PI

Dr Ann Lockman

Consultant in Acute Medicine

Research Team

Julia Grahamslaw

Lead Research Nurse

Caroline Blackstock

AMU Senior Research Nurse

Bev Goldberg

AMU Senior Research Nurse

Rachel O'Brien

Lead Research Nurse

More EMERGE Trials

The study with PP100-01 in combination with NAC is designed to determine safety and tolerability of PP100-01 when co-administered with NAC as compared to the 12-hr NAC treatment regime for patients that come to the hospital after an overdose of paracetamol/acetaminophen.

Read more

The POP Trial

A Randomised Open Label Exploratory, Safety and Tolerability Study with PP100-01 in Patients Treated with the 12-hour Regimen of N-Acetylcysteine for Paracetamol/Acetaminophen Overdose

Global Anticoagulant Registry in the FIELD observing treatment and outcomes in patients with treated acute Venous Thromboembolic Events in the real world

Read more

Garfield-VTE

Global Anticoagulant Registry In the FIELD – Venous Thromboembolic Events

MAPP2

The Markers and Paracetamol Poisoning Study 2