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Start date:
October 2013
End date:
February 2018
Co-ordinated by:
University of Nottingham
Main trial site:

Tranexamic Acid for Hyperacute Primary IntraCerebral Haemorrhage


To assess whether tranexamic acid is safe and reduces death and dependency after hyperacute (within 8 hours of onset) spontaneous intracerebral haemorrhage.

Trial Design

A phase III prospective pragmatic double blind randomised placebo controlled trial

Chief Investigator

Dr Nikola Sprigg (Medical expert) Clinical Associate Professor, University of Nottingham

Principal Investigator

Professor Rustam Al-Shahi Salman, Professor of clinical neurology, University of Edinburgh & NHS Lothian

Local lead in ED

Dr Matt Reed is the local contact for recruitment of ED patients into the study.

Research Team

  • EMERGE Research team
  • Stroke Research Group

Eligibility criteria (summary)

Patients who present to the ED within 8 hours of acute spontaneous intracerebral haemorrhagic stroke.

Further information

For more information please refer to main trial website

Research Team

Dr Matt Reed

Consultant and NRS Career Research Fellow in Emergency Medicine

Bernadette Gallagher

Senior Research Nurse

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