A randomised trial of intravenous or nebulised magnesium sulphate versus placebo for acute severe asthma.
To assess the effectiveness of IV and nebulised magnesium sulphate in the treatment of acute severe asthma.
Multi centre randomised controlled trial of intravenous (IV) or nebulised magnesium sulphate versus placebo for acute severe asthma
Professor Steve Goodacre
Professor Alasdair Gray
S Goodacre, J Cohen, M Bradburn, A Gray, J Benger, T Coats on behalf of the 3Mg Research Team. The 3Mg Trial: Randomised controlled trial of intravenous or nebulised magnesium sulphate or standard therapy for severe acute asthma. The Lancet Respiratory Medicine. (2013); 1:293 – 300.
Goodacre S, Cohen J, Bradburn M, Stevens J, Gray A, Benger J, et al. The 3Mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma. . Health Technology Assessment. (2014);18(22).
This is a study looking at incidence and risk factors for poor ankle functional recovery, and the development and progression of post-traumatic ankle osteoarthritis after significant ankle ligament injury.
SALI study - Significant Ankle Ligament Injury
This trial is a two arm, multicentre parallel group, randomised controlled, open label trial comparing intravenous levetiracetam to intravenous phenytoin for the treatment of convulsive status epilepticus (CSE) in children, young people and young adults.
Emergency Treatment with Levetiracetam or Phenytoin in Status Epilepticus in Children (EcLiPSE) – an open label randomised controlled trial